The Human CD21 Monoclonal Antibody (BU32) is a premium research tool offered by Assay Genie for scientists studying CD21, a crucial cell surface protein involved in the immune response. This monoclonal antibody, clone BU32, is specifically designed for use in various research applications to detect and analyze the CD21 protein in human samples.CD21, also known as complement receptor 2 (CR2), is a key molecule involved in immune regulation, particularly in the activation of B-cells and the adaptive immune response. By targeting CD21, researchers can gain valuable insights into how this protein influences immune function and its role in diseases such as autoimmune disorders, infectious diseases, and immune-related cancers.
The Human CD21 Monoclonal Antibody (BU32) is rigorously validated for its specificity and sensitivity in immunological assays, including flow cytometry, immunohistochemistry, and Western blotting. This antibody offers researchers a reliable tool for investigating the expression, localization, and function of CD21 in various cell types and experimental conditions.Whether exploring the role of CD21 in vaccine development, autoimmune diseases, or immunotherapy, the Human CD21 Monoclonal Antibody (BU32) from Assay Genie provides researchers with a high-quality reagent to advance their understanding of immune system regulation and related pathologies.
Product Title:
Purified Anti-Human CD21 Antibody [BU32]
SKU:
AGEL0201
Size:
25µg, 100µg
Clone No:
BU32
Synonyms:
Complement receptor type 2;CR2;Cr2;Complement C3d receptor;Epstein-Barr virus receptor;EBV receptor;CD21;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG1, κ
Isotype Control:
Purified Mouse IgG1, κ Isotype Control[MOPC-21]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD21 is a 145 kD transmembrane protein also known as complement C3d receptor (C3dR), complement receptor 2 (CR2), and Epstein-Barr virus receptor. CD21 is expressed on B cells, follicular dendritic cells, subsets of normal thymocytes and T cells, and some epithelial cells. CD21 is the receptor used by Epstein-Barr virus to infect B cells and is also the complement receptor for C3d. CD21 has also been shown to interact with a number of proteins, including CD23, CD19, annexin VI, CD81, iC3b, complement receptor 1 (CR1, CD35), and interferon-alpha 1 (IFN-α1).
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