Human ABHD14B Recombinant Protein (RPPB5763)
- SKU:
- RPPB5763
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96IU4
- Research Area:
- Enzymes
Description
| Product Name: | Human ABHD14B Recombinant Protein |
| Product Code: | RPPB5763 |
| Size: | 5µg |
| Species: | Human |
| Target: | ABHD14B |
| Synonyms: | Abhydrolase domain containing protein 14B, CIB, CCG1-interacting factor B, cell cycle gene 1-interacting factor B, EC 3.1.11.6, EC 3.1.21.4. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The ABHD14B solution (0.5mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl, 1mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMAASVE QREGTIQVQG QALFFREALP GSGQARFSVL LLHGIRFSSE TWQNLGTLHR LAQAGYRAVA IDLPGLGHSK EAAAPAPIGE LAPGSFLAAV VDALELGPPV VISPSLSGMY SLPFLTAPGS QLPGFVPVAP ICTDKINAAN YASVKTPALI VYGDQDPMGQ TSFEHLKQLP NHRVLIMKGA GHPCYLDKPE EWHTGLLDFL QGLQ |
ABHD14B is a member of the AB hydrolase superfamily. ABHD14B has an alpha/beta hydrolase fold - a catalytic domain found in a large number of enzymes. In molecular biology, the alpha/beta hydrolase fold is common to a number of hydrolytic enzymes of broad differing phylogenetic source and catalytic function. The Ab hydrolase domain containing gene subfamily includes 15 mostly uncharacterized members. ABHD14B has hydrolase activity with p-nitrophenyl butyrate (in vitro) and is able to activate transcription.
ABHD14B Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 234 amino acids (1-210) and having a molecular mass of 25.0kDa.ABHD14B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ABHD14B: Has hydrolase activity towards p-nitrophenyl butyrate (in vitro). May activate transcription. Belongs to the AB hydrolase superfamily. ABHD14 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 3.-.-.-; Hydrolase Chromosomal Location of Human Ortholog: 3p21.2 Cellular Component: cytoplasm; nucleolus; cytosol; nucleus Molecular Function:protein binding; hydrolase activity Biological Process: metabolic process; positive regulation of transcription from RNA polymerase II promoter |
| UniProt Code: | Q96IU4 |
| NCBI GenInfo Identifier: | 34222621 |
| NCBI Gene ID: | 84836 |
| NCBI Accession: | Q96IU4.1 |
| UniProt Secondary Accession: | Q96IU4,Q86VK8, Q8N8W5, |
| UniProt Related Accession: | Q96IU4 |
| Molecular Weight: | 210 |
| NCBI Full Name: | Alpha/beta hydrolase domain-containing protein 14B |
| NCBI Synonym Full Names: | abhydrolase domain containing 14B |
| NCBI Official Symbol: | ABHD14B�� |
| NCBI Official Synonym Symbols: | CIB; HEL-S-299�� |
| NCBI Protein Information: | alpha/beta hydrolase domain-containing protein 14B; CCG1-interacting factor B; epididymis secretory protein Li 299; cell cycle gene 1-interacting factor B; abhydrolase domain-containing protein 14B |
| UniProt Protein Name: | Alpha/beta hydrolase domain-containing protein 14B |
| UniProt Synonym Protein Names: | CCG1-interacting factor B |
| Protein Family: | Protein |
| UniProt Gene Name: | ABHD14B�� |
| UniProt Entry Name: | ABHEB_HUMAN |
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