Human ACYP1 Recombinant Protein (RPPB5786)
- SKU:
- RPPB5786
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P07311
- Research Area:
- Enzymes
Description
| Product Name: | Human ACYP1 Recombinant Protein |
| Product Code: | RPPB5786 |
| Size: | 20µg |
| Species: | Human |
| Target: | ACYP1 |
| Synonyms: | Acylphosphatase-1, Acylphosphatase, erythrocyte isozyme, Acylphosphatase, organ-common type isozyme, Acylphosphate phosphohydrolase 1, ACYP1, ACYPE. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The ACYP1 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAEGNTL ISVDYEIFGK VQGVFFRKHT QAEGKKLGLV GWVQNTDRGT VQGQLQGPIS KVRHMQEWLE TRGSPKSHID KANFNNEKVI LKLDYSDFQI VK |
Erythrocyte acylphosphatase (ACYP1) is a cytosolic enzyme which catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. There are two acylphophatase isoenzymes: ACYP1 and ACYP2. These isoenzymes share 60% homology and have the same substrate specificity, even though ACYP1 has a higher catalytic activity than ACYP2.
ACYP1 Human Recombinant fused with a�23 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing�122 amino acids (1-99 a.a.) and having a molecular mass of 13.6kDa. The ACYP1 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ACYP1: Its physiological role is not yet clear. Belongs to the acylphosphatase family. |
| UniProt Protein Details: | Protein type:Hydrolase; Motility/polarity/chemotaxis; Carbohydrate Metabolism - pyruvate; EC 3.6.1.7 Chromosomal Location of Human Ortholog: 14q24.3 Biological Process: phosphate metabolic process |
| NCBI Summary: | This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014] |
| UniProt Code: | P07311 |
| NCBI GenInfo Identifier: | 2507560 |
| NCBI Gene ID: | 97 |
| NCBI Accession: | P07311.2 |
| UniProt Secondary Accession: | P07311,A6NDV8, B2R590, |
| UniProt Related Accession: | P07311 |
| Molecular Weight: | 6,113 Da |
| NCBI Full Name: | Acylphosphatase-1 |
| NCBI Synonym Full Names: | acylphosphatase 1 |
| NCBI Official Symbol: | ACYP1�� |
| NCBI Official Synonym Symbols: | ACYPE�� |
| NCBI Protein Information: | acylphosphatase-1 |
| UniProt Protein Name: | Acylphosphatase-1 |
| UniProt Synonym Protein Names: | Acylphosphatase, erythrocyte isozyme; Acylphosphatase, organ-common type isozyme; Acylphosphate phosphohydrolase 1 |
| Protein Family: | Acylphosphatase |
| UniProt Gene Name: | ACYP1�� |
| UniProt Entry Name: | ACYP1_HUMAN |
