Human LGALSL Recombinant Protein (RPPB3858)
- SKU:
- RPPB3858
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q3ZCW2
Description
| Product Name: | Human LGALSL Recombinant Protein |
| Product Code: | RPPB3858 |
| Size: | 10µg |
| Species: | Human |
| Target: | LGALSL |
| Synonyms: | GRP, HSPC159, Galectin-related protein, Lectin galactoside-binding-like protein, LGALSL. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | LGALSL protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMAGSVAD SDAVVKLDDG HLNNSLSSPV QADVYFPRLI VPFCGHIKGG MRPGKKVLVM GIVDLNPESF AISLTCGDSE DPPADVAIEL KAVFTDRQLL RNSCISGERG EEQSAIPYFP FIPDQPFRVE ILCEHPRFRV FVDGHQLFDF YHRIQTLSAI DTIKINGDLQ ITKLG |
Galectins are a family of soluble b-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix interactions. Galectins also take part in tumor progression, pre-mRNA splicing and apoptosis. Galectin-related protein (LGALSL) is a 172 amino acid protein which holds one galectin domain. In spite of this, LGALSL does not appear to bind carbohydrates or lactose since the critical residues required for binding are not conserved.
LGALSL Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 195 amino acids (1-172a.a) and having a molecular mass of 21.4kDa. LGALSL is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | HSPC159: Does not bind lactose, and may not bind carbohydrates. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 2p14 Cellular Component: intracellular Molecular Function:protein binding |
| UniProt Code: | Q3ZCW2 |
| NCBI GenInfo Identifier: | 166223243 |
| NCBI Gene ID: | 29094 |
| NCBI Accession: | Q3ZCW2.2 |
| UniProt Secondary Accession: | Q3ZCW2,Q6P5T6, Q9P005, B2RBG8, D6W5E8, |
| UniProt Related Accession: | Q3ZCW2 |
| Molecular Weight: | 18,986 Da |
| NCBI Full Name: | Galectin-related protein |
| NCBI Synonym Full Names: | galectin like |
| NCBI Official Symbol: | LGALSL�� |
| NCBI Official Synonym Symbols: | GRP; HSPC159�� |
| NCBI Protein Information: | galectin-related protein |
| UniProt Protein Name: | Galectin-related protein |
| UniProt Synonym Protein Names: | Lectin galactoside-binding-like protein |
| Protein Family: | Galectin-related protein |
| UniProt Gene Name: | LGALSL�� |
| UniProt Entry Name: | LEGL_HUMAN |
