Human NARS Recombinant Protein (RPPB2000)
- SKU:
- RPPB2000
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O43776
- Research Area:
- Enzymes
Description
| Product Name: | Human NARS Recombinant Protein |
| Product Code: | RPPB2000 |
| Size: | 10µg |
| Species: | Human |
| Target: | NARS |
| Synonyms: | NARS, Asparaginyl-TRNASynthetase, AsnRS,EC 6.1.1.22, Asparaginyl-TRNA Synthetase, Cytoplasmic, Asparagine TRNALigase 1, Cytoplasmic, Asparagine--TRNA Ligase, Cytoplasmic, AsparagineTRNA Ligase 1, Cytoplasmic, NARS1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | NARSprotein solution (0.25mg/ml) containing Phosphate Buffered Saline (pH7.4) and 10%glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greaterthan 80.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | GSSHHHHHH SSGLVPRGSH MGSMVLAELY VSDREGSDAT GDGTKEKPFK TGLKALMTVG KEPFPTIYVDSQKENERWNV ISKSQLKNIK KMWHREQMKS ESREKKEAED SLRREKNLEE AKKITIKNDP SLPEPKCVKIGALEGYRGQR VKVFGWVHRL RRQGKNLMFL VLRDGTGYLQ CVLADELCQC YNGVLLSTES SVAVYGMLNL TPKGKQAPGG HELSCDFWELIGLAPAGGAD NLINEESDVD VQLNNRHMMI RGENMSKILK ARSMVTRCFR DHFFDRGYYE VTPPTLVQTQVEGGATLFKL DYFGEEAFLT QSSQLYLETC LPALGDVFCI AQSYRAEQSR TRRHLAEYTH VEAECPFLTF DDLLNRLEDL VCDVVDRILK SPAGSIVHEL NPNFQPPKRPFKRMNYSDAI VWLKEHDVKK EDGTFYEFGE DIPEAPERLM TDTINEPILL CRFPVEIKSF YMQRCPEDSRLTESVDVLMP NVGEIVGGSM RIFDSEEILA GYKREGIDPT PYYWYTDQRK YGTCPHGGYG LGLERFLTWILNRYHIRDVC LYPRFVQRCT P |
Aminoacyl-tRNA synthetases are a class of enzymes which charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase (NARS) is localized to the cytoplasm and is a member of the class II family of tRNA synthetases. The N-terminal domain characterizes the signature sequence for the eukaryotic asparaginyl-tRNA synthetases.
NARS Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 571 amino acids (1-548 a.a) andhaving a molecular mass of 65.3kDa. NARS is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.
| UniProt Protein Function: | NARS: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases. The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Translation; EC 6.1.1.22; Ligase Chromosomal Location of Human Ortholog: 18q21.31 Cellular Component: mitochondrion; cytoplasm; cytosol Molecular Function:nucleic acid binding; asparagine-tRNA ligase activity; ATP binding Biological Process: asparaginyl-tRNA aminoacylation; tRNA aminoacylation for protein translation; gene expression |
| NCBI Summary: | Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Asparaginyl-tRNA synthetase is localized to the cytoplasm and belongs to the class II family of tRNA synthetases. The N-terminal domain represents the signature sequence for the eukaryotic asparaginyl-tRNA synthetases. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43776 |
| NCBI GenInfo Identifier: | 3915059 |
| NCBI Gene ID: | 4677 |
| NCBI Accession: | O43776.1 |
| UniProt Secondary Accession: | O43776,Q53GU6, B4DG16, |
| UniProt Related Accession: | O43776 |
| Molecular Weight: | 548 |
| NCBI Full Name: | Asparagine--tRNA ligase, cytoplasmic |
| NCBI Synonym Full Names: | asparaginyl-tRNA synthetase |
| NCBI Official Symbol: | NARS�� |
| NCBI Official Synonym Symbols: | ASNRS; NARS1�� |
| NCBI Protein Information: | asparagine--tRNA ligase, cytoplasmic; asparagine tRNA ligase 1, cytoplasmic; asparaginyl-tRNA synthetase, cytoplasmic |
| UniProt Protein Name: | Asparagine--tRNA ligase, cytoplasmic |
| UniProt Synonym Protein Names: | Asparaginyl-tRNA synthetase; AsnRS |
| Protein Family: | Probable sensor histidine kinase |
| UniProt Gene Name: | NARS�� |
| UniProt Entry Name: | SYNC_HUMAN |
