Human PECR Recombinant Protein (RPPB2091)
- SKU:
- RPPB2091
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BY49
- Research Area:
- Enzymes
Description
| Product Name: | Human PECR Recombinant Protein |
| Product Code: | RPPB2091 |
| Size: | 20µg |
| Species: | Human |
| Target: | PECR |
| Synonyms: | Peroxisomal trans-2-enoyl-CoA reductase, TERP, HSA250303, SDR29C1, 2,4-dienoyl-CoA reductase-related protein, DCR-RP, pVI-ARL, EC 1.3.1.38, HPDHASE, putative short chain alcohol dehydrogenase, short chain dehydrogenase/reductase family 29C member 1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The PECR solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 2mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMASWAK GRSYLAPGLL QGQVAIVTGG ATGIGKAIVK ELLELGSNVV IASRKLERLK SAADELQANL PPTKQARVIP IQCNIRNEEE VNNLVKSTLD TFGKINFLVN NGGGQFLSPA EHISSKGWHA VLETNLTGTF YMCKAVYSSW MKEHGGSIVN IIVPTKAGFP LAVHSGAARA GVYNLTKSLA LEWACSGIRI NCVAPGVIYS QTAVENYGSW GQSFFEGSFQ KIPAKRIGVP EEVSSVVCFL LSPAASFITG QSVDVDGGRS LYTHSYEVPD HDNWPKGAGD LSVVKKMKET FKEKAKL |
PECR is the main enzyme for a projected peroxisomal chain elongation pathway and is primarily expressed in kidney and liver.
PECR Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 327 amino acids (1-303) and having a molecular mass of 35.1 kDa.PECR is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PECR: Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 1.3.1.38; Lipid Metabolism - unsaturated fatty acid biosynthesis; Oxidoreductase Chromosomal Location of Human Ortholog: 2q35 Cellular Component: peroxisomal membrane; intracellular membrane-bound organelle; mitochondrion; peroxisome Molecular Function:2,4-dienoyl-CoA reductase (NADPH) activity; receptor binding; trans-2-enoyl-CoA reductase (NADPH) activity Biological Process: phytol metabolic process; fatty acid biosynthetic process |
| UniProt Code: | Q9BY49 |
| NCBI GenInfo Identifier: | 62287123 |
| NCBI Gene ID: | 55825 |
| NCBI Accession: | Q9BY49.2 |
| UniProt Secondary Accession: | Q9BY49,Q53TC4, Q6IAK9, Q9NRD4, Q9NY60, Q9P1A4, B2RE42 |
| UniProt Related Accession: | Q9BY49 |
| Molecular Weight: | 303 |
| NCBI Full Name: | Peroxisomal trans-2-enoyl-CoA reductase |
| NCBI Synonym Full Names: | peroxisomal trans-2-enoyl-CoA reductase |
| NCBI Official Symbol: | PECR�� |
| NCBI Official Synonym Symbols: | TERP; DCRRP; PVIARL; HPDHASE; SDR29C1; HSA250303�� |
| NCBI Protein Information: | peroxisomal trans-2-enoyl-CoA reductase; DCR-RP; pVI-ARL; 2,4-dienoyl-CoA reductase-related protein; putative short chain alcohol dehydrogenase; short chain dehydrogenase/reductase family 29C, member 1 |
| UniProt Protein Name: | Peroxisomal trans-2-enoyl-CoA reductase |
| UniProt Synonym Protein Names: | 2,4-dienoyl-CoA reductase-related protein; DCR-RP; HPDHase; pVI-ARL |
| Protein Family: | Peroxisomal trans-2-enoyl-CoA reductase |
| UniProt Gene Name: | PECR�� |
| UniProt Entry Name: | PECR_HUMAN |
