Human PPP3R2 Recombinant Protein (RPPB2172)
- SKU:
- RPPB2172
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96LZ3
- Research Area:
- Enzymes
Description
| Product Name: | Human PPP3R2 Recombinant Protein |
| Product Code: | RPPB2172 |
| Size: | 20µg |
| Species: | Human |
| Target: | PPP3R2 |
| Synonyms: | Calcineurin subunit B type 2, Calcineurin B-like protein, CBLP, Calcineurin BII, CNBII, PPP3R1-like, Protein phosphatase 2B regulatory subunit 2, Protein phosphatase 3 regulatory subunit B beta isoform, PPP3R2, PPP3RL. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The PPP3R2 solution (0.5mg/ml) contains 20mM Tris-HCl buffer(pH 8.0), 10% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MSTMGNEASY PAEMCSHFDN DEIKRLGRRF KKLDLDKSGS LSVEEFMSLP ELRHNPLVRR VIDVFDTDGD GEVDFKEFIL GTSQFSVKGD EEQKLRFAFS IYDMDKDGYI SNGELFQVLK MMVGNNLTDW QLQQLVDKTI IILDKDGDGK ISFEEFSAVV RDLEIHKKLV LIV |
PPP3R2 is a calcium-dependent, calmodulin stimulated serine/threonine protein phosphatase. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is a crucial means of regulating a wide range of cellular functions including division, homeostasis and apoptosis. Ordinarily the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit.
PPP3R2 Human Recombinant fused with a 20 a.a. His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain (a.a. 1-173) containing 193 amino acids and having a molecular mass of 22kDa.The PPP3R2 is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PPP3R2: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. Belongs to the calcineurin regulatory subunit family. |
| UniProt Protein Details: | Protein type:Protein phosphatase, regulatory subunit Chromosomal Location of Human Ortholog: 9q31.1 Molecular Function:calcium ion binding |
| UniProt Code: | Q96LZ3 |
| NCBI GenInfo Identifier: | 52000731 |
| NCBI Gene ID: | 5535 |
| NCBI Accession: | Q96LZ3.3 |
| UniProt Related Accession: | Q96LZ3 |
| Molecular Weight: | |
| NCBI Full Name: | Calcineurin subunit B type 2 |
| NCBI Synonym Full Names: | protein phosphatase 3 regulatory subunit B, beta |
| NCBI Official Symbol: | PPP3R2�� |
| NCBI Official Synonym Symbols: | PPP3RL�� |
| NCBI Protein Information: | calcineurin subunit B type 2 |
| UniProt Protein Name: | Calcineurin subunit B type 2 |
| UniProt Synonym Protein Names: | Calcineurin B-like protein; CBLP; Calcineurin BII; CNBII; PPP3R1-like; Protein phosphatase 2B regulatory subunit 2; Protein phosphatase 3 regulatory subunit B beta isoform |
| UniProt Gene Name: | PPP3R2�� |
| UniProt Entry Name: | CANB2_HUMAN |
