IKZF4 Antibody (PACO20958)
- SKU:
- PACO20958
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | IKZF4 Antibody (PACO20958) |
| Antibody SKU: | PACO20958 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:20-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human IKZF4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO20958(IKZF4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20958(IKZF4 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development. |
| Synonyms: | IKAROS family zinc finger 4 (Eos) |
| UniProt Protein Function: | IKZF4: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Belongs to the Ikaros C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; Transcription factor; DNA-binding Chromosomal Location of Human Ortholog: 12q13 Cellular Component: nucleus Molecular Function:protein homodimerization activity; sequence-specific DNA binding; protein heterodimerization activity; metal ion binding; bHLH transcription factor binding; transcription factor activity Biological Process: transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent |
| NCBI Summary: | Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002] |
| UniProt Code: | Q9H2S9 |
| NCBI GenInfo Identifier: | 122891864 |
| NCBI Gene ID: | 64375 |
| NCBI Accession: | NP_071910.3 |
| UniProt Related Accession: | Q9H2S9 |
| Molecular Weight: | |
| NCBI Full Name: | zinc finger protein Eos isoform a |
| NCBI Synonym Full Names: | IKAROS family zinc finger 4 |
| NCBI Official Symbol: | IKZF4Â Â |
| NCBI Official Synonym Symbols: | EOS; ZNFN1A4Â Â |
| NCBI Protein Information: | zinc finger protein Eos |
| UniProt Protein Name: | Zinc finger protein Eos |
| UniProt Synonym Protein Names: | Ikaros family zinc finger protein 4 |
| Protein Family: | Eosinophil peroxidase |
| UniProt Gene Name: | IKZF4Â Â |
| UniProt Entry Name: | IKZF4_HUMAN |
| Antibodies | ELISA Kits |
| IKZF4 Antibody (PACO05030) | IKZF4 Transcription Factor Activity Assay |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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