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[KO Validated] AIP Rabbit Polyclonal Antibody (CAB19969)

SKU:
CAB19969
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:[KO Validated] AIP Rabbit Polyclonal Antibody
SKU:CAB19969
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-330 of human AIP (NP_003968.3).
Sequence:MADI IARL REDG IQKR VIQE GRGE LPDF QDGT KATF HYRT LHSD DEGT VLDD SRAR GKPM ELII GKKF KLPV WETI VCTM REGE IAQF LCDI KHVV LYPL VAKS LRNI AVGK DPLE GQRH CCGV AQMR EHSS LGHA DLDA LQQN PQPL IFHM EMLK VESP GTYQ QDPW AMTD EEKA KAVP LIHQ EGNR LYRE GHVK EAAA KYYD AIAC LKNL QMKE QPGS PEWI QLDQ QITP LLLN YCQC KLVV EEYY EVLD HCSS ILNK YDDN VKAY FKRG KAHA AVWN AQEA QADF AKVL ELDP ALAP VVSR ELRA LEAR IRQK DEED KARF RGIF SH
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:ARA9; XAP2; PITA1; XAP-2; FKBP16; FKBP37; SMTPHN; IP
Positive Sample:HeLa
Conjugate:Unconjugated
Cellular Localization:Cytoplasm.
Calculated MW:38kDa
Observed MW:35kDa

The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus. Three transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:9049
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from wild type (WT) and AIP knockout (KO) HeLa cells, using [KO Validated] AIP Rabbit pAb (CAB19969) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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