Anti-LAMP1 Antibody (CAB11468)

Antibody Name:	Anti-LAMP1 Antibody
Antibody SKU:	CAB11468
Antibody Size:	20uL, 50uL, 100uL
Application:	WB IF
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human LAMP1 (NP_005552.3).

Application:	WB IF
Recommended Dilution:	WB 1:500 - 1:2000 IF 1:50 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:	Mouse liver

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 80-280 of human LAMP1 (NP_005552.3).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	CGKE NTSD PSLV IAFG RGHT LTLN FTRN ATRY SVQL MSFV YNLS DTHL FPNA SSKE IKTV ESIT DIRA DIDK KYRC VSGT QVHM NNVT VTLH DATI QAYL SNSS FSRG ETRC EQDR PSPT TAPP APPS PSPS PVPK SPSV DKYN VSGT NGTC LLAS MGLQ LNLT YERK DNTT VTRL LNIN PNKT SASG SCGA HLVT LELH S
Gene ID:	3916
Uniprot:	P11279
Cellular Location:	Cell membrane, Endosome membrane, Late endosome, Lysosome membrane, Single-pass type I membrane protein
Calculated MW:	38kDa/44kDa
Observed MW:	45kDa/120kDa

Synonyms:	LAMP1, CD107a, LAMPA, LGP120
Background:	The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis.

UniProt Protein Function:	LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family.
UniProt Protein Details:	Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 13q34 Cellular Component: integral to plasma membrane; lysosome; dendrite; multivesicular body; cell soma; membrane; late endosome; cytoplasm; plasma membrane; melanosome; endosome membrane; sarcolemma; external side of plasma membrane Molecular Function:protein domain specific binding; protein binding; enzyme binding Biological Process: positive regulation of natural killer cell degranulation; induction of apoptosis by granzyme; protein stabilization; viral reproduction; autophagic cell death; autophagy; positive regulation of natural killer cell mediated cytotoxicity
NCBI Summary:	The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]
UniProt Code:	P11279
NCBI GenInfo Identifier:	206729915
NCBI Gene ID:	3916
NCBI Accession:	P11279.3
UniProt Secondary Accession:	P11279,Q8WU33, Q96I40, Q9BRD2, Q9NP13, B4DWL3,
UniProt Related Accession:	P11279
Molecular Weight:	417
NCBI Full Name:	Lysosome-associated membrane glycoprotein 1
NCBI Synonym Full Names:	lysosomal-associated membrane protein 1
NCBI Official Symbol:	LAMP1
NCBI Official Synonym Symbols:	LAMPA; CD107a; LGP120
NCBI Protein Information:	lysosome-associated membrane glycoprotein 1; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1
UniProt Protein Name:	Lysosome-associated membrane glycoprotein 1
UniProt Synonym Protein Names:	CD107 antigen-like family member A; CD_antigen: CD107a
Protein Family:	Lysosome-associated membrane glycoprotein
UniProt Gene Name:	LAMP1
UniProt Entry Name:	LAMP1_HUMAN

	Western blot analysis of extracts of mouse liver, using LAMP1 antibody (CAB11468) at 1:500 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
	Immunofluorescence analysis of HeLa cells using LAMP1 antibody (CAB11468) at dilution of 1:100. Blue: DAPI for nuclear staining.
	Immunofluorescence analysis of NIH/3T3 cells using LAMP1 antibody (CAB11468) at dilution of 1:100. Blue: DAPI for nuclear staining.

Antibodies

Human CD107a/LAMP-1 Monoclonal Antibody (FITC Conjugated) [H4A3](AGEL1774)

Human CD107a/LAMP-1 Monoclonal Antibody (PE Conjugated) [H4A3](AGEL1775)

Human CD107a/LAMP-1 Monoclonal Antibody (APC Conjugated) [H4A3](AGEL1776)

Anti-LAMP1 Antibody (CAB16894)

Anti-LAMP1 Antibody (CAB16895)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)