The Lumican (LUM) Monoclonal Antibody (CAB11593) is a high-quality antibody developed for reliable detection and analysis of target proteins. Lumican is a member of the small leucine-rich proteoglycan family and is involved in extracellular matrix organization and cell adhesion.This antibody, generated in rabbits, exhibits high specificity and sensitivity for Lumican in human samples. It is suitable for use in applications such as Western blotting, immunohistochemistry, and immunofluorescence, allowing for the detection and analysis of Lumican in different cell types and tissues.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
Lumican (LUM) Monoclonal Antibody
SKU:
CAB11593
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Clone Number:
ARC0637
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.
Purification Method
Affinity purification
Gene ID
4060
RRID
AB_2861602
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Lumican (LUM) (LUM) Rabbit mAb (CAB11593) at 1：1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 5s.
Immunohistochemistry analysis of paraffin-embedded Human colon using Lumican (LUM) (LUM) Rabbit mAb (CAB11593) at dilution of 1:100 (40x lens). Microwave antigen retrieval performed with 0.01M PBS Buffer (pH 7.2) prior to IHC staining.
