null

MAPK6 Antibody (PACO07004)

SKU:
PACO07004
Product Type:
Antibody
Host Species:
Rabbit
Reactivity:
Human, Mouse, Rat
Size:
50 µg
Target:
MAPK6
  • Immunohistochemical analysis of paraffin-embedded human Breast caricnoma using ERK 3 Polyclonal Antibody. MAPK6 Antibody (PACO07004)
  • Western blot analysis of 1) Hela, 2) 293T, 3) 3T3, 4) Rat Brain using ERK 3 Polyclonal Antibody. MAPK6 Antibody (PACO07004)
€188
Frequently bought together:

Description

system_update_altMSDS
Antibody Name: MAPK6 Antibody
Antibody SKU: PACO07004
Size: 50 µg
Target Name: MAPK6
Host Species: Rabbit
Tested Applications: WB
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant Protein
Immunogen Species: Homo sapiens (Human)
Form: Liquid
Storage Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Conjugate: Non-conjugated
Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Isotype: IgG
Recommended Dilution:
Application Recommended Dilution
WB 1:500-1000
IHC 1:200-500
Synonyms: ERK-3 antibody; ERK3 antibody; Extracellular signal regulated kinase 3 antibody; Extracellular signal regulated kinase p97 antibody; Extracellular signal-regulated kinase 3 antibody; HsT17250 antibody; MAP kinase 6 antibody; MAP kinase isoform p97 antibody; MAPK 6 antibody; MAPK6 antibody; Mitogen activated protein kinase 6 antibody; Mitogen-activated protein kinase 6 antibody; MK06_HUMAN antibody; p97 MAPK antibody; p97-MAPK antibody; PRKM6 antibody; Protein kinase mitogen activated 5 antibody; Protein kinase mitogen activated 6 antibody
UniProt Code: Q16659
Target Background Function: Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle.
Subcellular Location: Cytoplasm. Nucleus.
Protein Families: Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MAP kinase subfamily
Tissue Specificity: Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.