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Biotin Anti-Mouse CD11a Antibody [FD441.8] (AGEL0153)

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SKU AGEL0153
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG2b
Clone FD441.8
Conjugation Biotin
Applications FC
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Description

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Biotin Anti-Mouse CD11a Antibody [FD441.8]

The Mouse CD11a Monoclonal Antibody (Biotin Conjugated) FD441/8 (AGEL0153) is a vital tool for researchers studying immune cell interactions and inflammatory responses. This antibody, derived from mouse hybridoma cells, specifically targets the CD11a protein, a key integrin involved in T-cell adhesion and signaling.CD11a, also known as αL integrin, plays a crucial role in mediating cell-cell interactions and promoting immune responses. By targeting CD11a with this monoclonal antibody, researchers can probe the function and regulation of this protein in various immune cell types. The biotin conjugation of this antibody allows for versatile detection methods, such as immunofluorescence and flow cytometry, enabling precise analysis of CD11a expression patterns in different experimental settings.

Understanding the role of CD11a in immune cell activation and migration can provide valuable insights into immune-related diseases, such as autoimmune disorders, inflammation, and infections. This antibody is a valuable tool for investigating the mechanisms underlying immune response modulation and developing targeted therapies for immune-mediated conditions.Overall, the Mouse CD11a Monoclonal Antibody FD441/8 (AGEL0153) is a reliable reagent for researchers seeking to explore the intricate functions of CD11a in immune system regulation and its implications for various pathological conditions.

Product Title:Biotin Anti-Mouse CD11a Antibody [FD441.8]
SKU:AGEL0153
Size:25µg, 100µg
Clone No:FD441.8
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Biotin Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P24063
Gene ID:16408
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

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