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Purified Anti-Mouse CD25 Antibody [PC-61.5.3] (AGEL0371)

Datasheet MSDS
SKU AGEL0371
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse
Host Species Rat
Isotype IgG1
Clone PC-61.5.3
Conjugation Unconjugated
Applications FC
€25 - €63

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Description

system_update_altDatasheetsystem_update_altMSDS

Purified Anti-Mouse CD25 Antibody [PC-61.5.3]

The Mouse CD25 Monoclonal Antibody (PC-61.5.3) from Assay Genie (AGEL0371) is a powerful tool for researchers studying immune responses and cell signaling pathways. This monoclonal antibody specifically targets CD25, also known as the interleukin-2 receptor alpha chain, which is crucial for regulating T cell activation and proliferation.Designed for use in various experimental applications, including flow cytometry, immunoprecipitation, and immunohistochemistry, this antibody offers high specificity and sensitivity in detecting CD25 expression in mouse samples. Its ability to bind to CD25 with precision allows for accurate analysis of T cells and their activation status, making it an essential tool for immunologists and cancer researchers.

CD25 plays a pivotal role in the immune system by controlling the activation and function of regulatory T cells, which are critical for maintaining immune tolerance and preventing autoimmune diseases. Dysregulation of CD25 expression has been implicated in various autoimmune disorders and cancers, highlighting its importance as a therapeutic target.By using the Mouse CD25 Monoclonal Antibody (PC-61.5.3), researchers can delve deeper into the mechanisms underlying immune responses, T cell function, and the development of immune-based therapies. With its reliability and versatility, this antibody enables precise detection and analysis of CD25 in mouse models, facilitating groundbreaking discoveries in immunology and cancer research.

Product Title:Purified Anti-Mouse CD25 Antibody [PC-61.5.3]
SKU:AGEL0371
Size:25µg, 100µg
Clone No:PC-61.5.3
Synonyms:Interleukin-2 receptor subunit alpha;IL2RA;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2-RA;TAC antigen;p55;p55;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG1, κ
Isotype Control:Purified Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:Unconjugated
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P01590
Gene ID:16184
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD25 is a 55 kD glycoprotein, also known as the low affinity IL-2Rα, Ly-43, p55, or Tac. It is expressed on activated T and B cells, thymocyte subset, pre-B cells, and T regulatory cells. In association with CD122 (IL-2Rβ) and CD132(common γ chain), CD25 forms the high affinity signaling IL-2 receptor.
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