Mouse CD93 Recombinant Protein (RPPB3102)
- SKU:
- RPPB3102
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- O89103
- Research Area:
- CD Antigens
Description
| Product Name: | Mouse CD93 Recombinant Protein |
| Product Code: | RPPB3102 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | CD93 |
| Synonyms: | C1q/MBL/SPAreceptor, C1qR(p), C1qRp, Cell surface antigen AA4, Complement, component 1 qsubcomponent receptor 1, Lymphocyte antigen 68, Ly-68, CD93, Cd93. |
| Source: | Sf9 Insect cells |
| Physical Appearance: | Sterilefiltered colorless solution. |
| Formulation: | CD93protein solution (0.5mg/ml) contains Phosphate Buffered Saline (pH 7.4) and 10%glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greaterthan 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | ADSQAVVCEG TACYTAHWGK LSAAEAQHRC NENGGNLATV KSEEEARHVQ QALTQLLKTK APLEAKMGKF WIGLQREKGN CTYHDLPMRG FSWVGGGEDT AYSNWYKASK SSCIFKRCVS LILDLSLTPH PSHLPKWHES PCGTPEAPGN SIEGFLCKFN FKGMCRPLAL GGPGRVTYTT PFQATTSSLE AVPFASVANV ACGDEAKSET HYFLCNEKTP GIFHWGSSGP LCVSPKFGCS FNNGGCQQDC FEGGDGSFRC GCRPGFRLLD DLVTCASRNP CSSNPCTGGG MCHSVPLSEN YTCRCPSGYQ LDSSQVHCVD IDECQDSPCA QDCVNTLGSF HCECWVGYQP SGPKEEACED VDECAAANSP CAQGCINTDG SFYCSCKEGY IVSGEDSTQC EDIDECSDAR GNPCDSLCFN TDGSFRCGCP PGWELAPNGV FCSRGTVFSE LPARPPQKED NDDRKESTMP PTEMPSSPSG SKDVSNRAQT TGLFVQSDIP TASVPLEIEI PSEVSDVWFE LGTYLPTTSG HSKPTHEDSV SAHSDTDGQN LEHHHHHH |
CD93, is a receptor or else an element of a larger receptor complex forC1q, MBL2-mannose-binding lectin and SPA-pulmonary surfactant protein A. CD93 mediates the enhancement of phagocytosis in monocytes as well asmacrophages upon interaction with soluble defense collagens. CD93 takes part in the intercellular adhesion.Furthermore, CD93 was expressed on (pre) plasmablasts/plasma cells, including long-lived plasma cells which demonstrated decreasedcell cycle activity, high levels of isotype-switched Ig secretion, as well asmodification of the transcriptional network. CD93 is vital for the maintenanceof plasma cells in bone marrow niches.
CD93 produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 558 amino acids (23-572a.a.) and having a molecular mass of 60.1kDa. (Molecular size on SDS-PAGE will appear at approximately 70-100kDa).�CD93 is expressed with an 8 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. Marker for early multipotent hematopoietic precursor cells. May play a role in cell-cell interactions during hematopoietic and vascular development. |
| UniProt Code: | O89103 |
| NCBI GenInfo Identifier: | 6754578 |
| NCBI Gene ID: | 17064 |
| NCBI Accession: | NP_034870 |
| UniProt Secondary Accession: | O89103,Q3U2X0, A2AVY5, |
| UniProt Related Accession: | O89103 |
| Molecular Weight: | 60.1kDa (558aa) 70-100KDa (SDS-PAGE under reducing conditions.) |
| NCBI Full Name: | complement component C1q receptor |
| NCBI Synonym Full Names: | CD93 antigen |
| NCBI Official Symbol: | Cd93�� |
| NCBI Official Synonym Symbols: | Ly68; AA4.1; C1qr1; C1qrp; AA145088; AW555904; 6030404G09Rik�� |
| NCBI Protein Information: | complement component C1q receptor |
| UniProt Protein Name: | Complement component C1q receptor |
| UniProt Synonym Protein Names: | C1q/MBL/SPA receptor; C1qR(p); C1qRp; Cell surface antigen AA4; Complement component 1 q subcomponent receptor 1; Lymphocyte antigen 68; Ly-68; CD_antigen: CD93 |
| Protein Family: | Complement component C1q receptor |
| UniProt Gene Name: | Cd93�� |
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