Mouse MIG Recombinant Protein (RPPB1210)
- SKU:
- RPPB1210
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- P18340
- Research Area:
- Chemokines
Description
| Product Name: | Mouse MIG Recombinant Protein |
| Product Code: | RPPB1210 |
| Size: | 20µg |
| Species: | Mouse |
| Target: | MIG |
| Synonyms: | Small inducible cytokine B9, CXCL9, MIG, chemokine (C-X-C motif) ligand 9, CMK, Humig, SCYB9, crg-10, M119. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | Filtered (0.2�m) and lyophilized from a concentrated (0.5mg/ml)solution in 20mM PB, pH7.4 and 100mM NaCl. |
| Solubility: | It is recommended to reconstitute the lyophilized MIG in sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized MIG although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CXCL9 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | The sequence of the first five N-terminal amino acids was determined and was found to be, Thr-Leu-Val-Ile-Arg |
| Biological Activity: | The Activity is calculated by the ability to chemoattractHuman lymphocytes using a concentration of 0.1-1 ng/ml. |
Chemokine (C-X-C motif) ligand 9 (CXCL9) is a small cytokine belonging to the CXC chemokine family that is also known as Monokine induced by MIG. CXCL9 is a T-cell chemoattractant. It is closely related to two other CXC chemokines called CXCL10 and CXCL11, whose genes are located near the gene for CXCL9 on human chromosome 4. CXCL9, CXCL10 and CXCL11 all elicit their chemotactic functions by interacting with the chemokine receptor CXCR3.
MIG (CXCK9) Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 105 amino acids and having a molecular mass of 12208 Dalton. The MIG is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CXCL9: Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis Cellular Component: extracellular space; extracellular region; external side of plasma membrane Molecular Function:CXCR3 chemokine receptor binding; chemokine activity; cytokine activity Biological Process: G-protein coupled receptor protein signaling pathway; positive regulation of leukocyte chemotaxis; immune response; response to lipopolysaccharide; chemotaxis; inflammatory response; defense response to virus; positive regulation of myoblast differentiation; regulation of cell proliferation |
| UniProt Code: | P18340 |
| NCBI GenInfo Identifier: | 408360042 |
| NCBI Gene ID: | 17329 |
| NCBI Accession: | P18340.2 |
| UniProt Secondary Accession: | P18340,Q8C9J0, Q99J60, |
| UniProt Related Accession: | P18340 |
| Molecular Weight: | 14,444 Da |
| NCBI Full Name: | C-X-C motif chemokine 9 |
| NCBI Synonym Full Names: | chemokine (C-X-C motif) ligand 9 |
| NCBI Official Symbol: | Cxcl9�� |
| NCBI Official Synonym Symbols: | CMK; Mig; MuMIG; Scyb9; crg-10; BB139920�� |
| NCBI Protein Information: | C-X-C motif chemokine 9; M119; protein m119; small-inducible cytokine B9; gamma interferon-induced monokine; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; small inducible cytokine B subfamily (Cys-X-Cys), member 9 |
| UniProt Protein Name: | C-X-C motif chemokine 9 |
| UniProt Synonym Protein Names: | Gamma-interferon-induced monokine; Monokine induced by interferon-gamma; MIG; MuMIG; Protein m119; Small-inducible cytokine B9 |
| Protein Family: | Migration and invasion enhancer |
| UniProt Gene Name: | Cxcl9�� |
| UniProt Entry Name: | CXCL9_MOUSE |
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