100% Quality Guarantee
PhD-Level Technical Support
Cell Cycle Antibodies 2 Anti-HEC1 Antibody CAB2392
Key Features

Anti-HEC1 Antibody (CAB2392)

Datasheet MSDS
SKU CAB2392
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human
Host Species Rabbit
Synonyms HEC, HEC1, TID3, KNTC2, HsHec1, hsNDC80, HEC1/NDC80
Research Use Cell Cycle
€131 - €457

Request a formal quotation

A PDF quote with its own quote number, ready for your purchasing office to raise a PO against. Back within 4 working hours, from a PhD scientist — not an autoresponder.

  • PO-ready PDFQuote number, VAT, Incoterms
  • Volume pricing appliedDiscounts from 2 kits up
  • Valid 30 daysPrices held while you get sign-off
Anything we should know? optional

No account needed. We use your details only to prepare and send this quote. If it's urgent, say so in the box and we'll come back the same working day.
Global Shipping: 80+ Countries
White Glove Service: Available upon request
Batch Consistency: Contact Sales
Distributors: 60+ Countries
Contact Sales Quote or discount
Find Distributor 50+ countries
Technical Support PhD-level team
Live Chat Available now

Description

system_update_altDatasheetsystem_update_altMSDS

HEC1/NDC80 Monoclonal Antibody (CAB2392)

The HEC1/NDC80 Monoclonal Antibody (CAB2392) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit monoclonal technology, offers high specificity and sensitivity for detecting HEC1 in various research applications, such as immunofluorescence and immunohistochemistry.HEC1 is a key component of the kinetochore, a protein complex essential for proper chromosome segregation during cell division. Dysregulation of HEC1 has been linked to chromosome instability and cancer development, making it a promising target for cancer research and drug development.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.

Product Name:HEC1/NDC80 Monoclonal Antibody
SKU:CAB2392
Size:20μL, 100μL
Reactivity:Human
Clone Number:ARC0741
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:Email for sequence
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:2000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:HEC, HEC1, TID3, KNTC2, HsHec1, hsNDC80, HEC1/NDC80
Positive Sample:HeLa, Jurkat
Cellular Localization:Chromosome, Nucleus, Centromere, Kinetochore.
Calculated MW:74kDa
Observed MW:76kDa

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation.

Purification MethodAffinity purification
Gene ID10403
RRIDAB_2862998
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using HEC1/NDC80 Rabbit mAb (CAB2392) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3 s.
View AllClose

0 Reviews

Write a Review
0
Based on 0 reviews

No reviews yet. Be the first to share your experience!

View AllClose

Related Products