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Signal Transduction Antibodies 3 Anti-PAIP1 Antibody CAB6042
Key Features

PAIP1 Rabbit Polyclonal Antibody (CAB6042)

Datasheet MSDS
SKU CAB6042
Product Type Antibody
Antibody Type Polyclonal Antibody
Reactivity Human, Mouse, Rat
Host Species Rabbit
Synonyms PAIP1
Research Use Signal Transduction
$127 - $488

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Description

system_update_altDatasheetsystem_update_altMSDS

PAIP1 Antibody (CAB6042)

The PAIP1 Antibody (CAB6042) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, raised in rabbits, is highly specific and reactive towards human samples, making it ideal for use in Western blot applications. By binding to the PAIP1 protein, this antibody enables researchers to detect and analyze PAIP1 expression in various cell types, offering insights into its functions in cellular processes.PAIP1 plays a crucial role in the regulation of protein synthesis by facilitating the interaction between poly(A)-binding protein (PABP) and eukaryotic translation initiation factor 4G (eIF4G). This interaction is essential for the translation of mRNA into proteins, highlighting the significance of PAIP1 in cellular function and homeostasis.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:PAIP1 Antibody
SKU:CAB6042
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:MSDG FDRA PEQT RPLR APPS SQDK IPQQ NSES AMAK PQVV VAPV LMSK LSVN APEF YPSG YSSS YTES YEDG CEDY PTLS EYVQ DFLN HLTE QPGS FETE IEQF AETL NGCV TTDD ALQE LVEL IYQQ ATSI PNFS YMGA RLCN YLSH HLTI SPQS GNFR QLLL QRCR TEYE VKDQ AAKG DEVT RKRF HAFV LFLG ELYL NLEI KGTN GQVT RADI LQVG LREL LNAL FSNP MDDN LICA VKLL KLTG SVLE DAWK EKGK
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:PAIP1
Positive Sample:HeLa, HepG2, A-549, 293T, BT-474, Mouse liver, Mouse kidney, Mouse brain, Rat brain
Cellular Localization:Cytoplasm.
Calculated MW:54kDa
Observed MW:70kDa

The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

Purification MethodAffinity purification
Gene ID10605
RRIDAB_2766725
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using PAIP1 Rabbit pAb (CAB6042) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
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