PE Anti-Human CD273/PD-L2 Antibody [24F.10C12] (AGEL1861)

PE Anti-Human CD273/PD-L2 Antibody [24F.10C12]

The Human CD273 (PD-L2) Monoclonal Antibody (PE Conjugated, 24F.10C12) is a cutting-edge tool for researchers studying the immune checkpoint protein PD-L2 in human samples. This monoclonal antibody, conjugated with phycoerythrin (PE), provides high specificity and sensitivity in flow cytometry and immunofluorescence applications, allowing for precise detection and analysis of PD-L2 expression on various cell types.PD-L2, also known as programmed death-ligand 2, is a key regulator of immune responses and tolerance. Its interaction with the PD-1 receptor on T cells plays a crucial role in modulating immune function and maintaining self-tolerance.

Dysregulation of the PD-L2/PD-1 pathway is implicated in conditions such as cancer, chronic infections, and autoimmune diseases, making PD-L2 an attractive target for therapeutic interventions.By utilizing the Human CD273 (PD-L2) Monoclonal Antibody (PE Conjugated, 24F.10C12), researchers can delve deeper into the mechanisms underlying immune tolerance and immune evasion in disease states. This antibody offers a valuable tool for investigating PD-L2 expression levels, distribution, and localization, ultimately contributing to the development of novel immunotherapies and precision medicine approaches targeting the PD-L2 pathway.

Isotype:	Mouse IgG2a, κ
Isotype Control:	PE Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:	Liquid
Conjugation:	PE
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum: