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Anti-Phospho-YAP1-S127 Antibody (CABP0489)

SKU:
CABP0489
Product Type:
Antibody
Applications:
WB
Reactivity:
Human
Mouse
Rat
Monkey
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-Phospho-YAP1-S127 Antibody CABP0489
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-Phospho-YAP1-S127 Antibody CABP0489
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-Phospho-YAP1-S127 Antibody CABP0489
  • Epigenetics and Nuclear Signaling Antibodies 4 Anti-Phospho-YAP1-S127 Antibody CABP0489
€329 - €419
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Description

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Antibody Name:Anti-Phospho-YAP1-S127 Antibody
Antibody SKU:CABP0489
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Reactivity:Human, Mouse, Rat
Positive Samples:NIH/3T3
Immunogen:A synthetic phosphorylated peptide around S127 of human YAP1 (NP_001123617.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:AHSS P
Gene ID:10413
Uniprot:P46937
Cellular Location:Cytoplasm, Nucleus
Calculated MW:36kDa/48kDa/49kDa/50kDa/52kDa/53kDa/54kDa
Observed MW:68kDa
Anti-Phospho-YAP1-S127 Antibody (CABP0489)Western blot analysis of extracts of NIH3T3†’†’€š cells, using Phospho-YAP1-S127 antibody (CABP0489) at 1:1000 dilution.NIH3T3 cells were treated by Sorbitol (0.2M) at 37'C for 60 minutes after serum-starvation overnight. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% BSA. Detection: ECL Enhanced Kit (RM00021). Exposure time: 60s.
Anti-Phospho-YAP1-S127 Antibody (CABP0489)Immunohistochemistry of paraffin-embedded human colon carcinoma using Phospho-YAP1-S127 Rabbit pAb (CABP0489) at dilution of 1:100 (40x lens).
Anti-Phospho-YAP1-S127 Antibody (CABP0489)Immunofluorescence analysis of HeLa cells using Phospho-YAP1-S127 Rabbit pAb (CABP0489) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Anti-Phospho-YAP1-S127 Antibody (CABP0489)Immunofluorescence analysis of NIH-3T3 cells using Phospho-YAP1-S127 Rabbit pAb (CABP0489) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Synonyms:COB1, YAP, YAP2, YAP65, YKI, YAP1
Background:This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
UniProt Code:P46937
NCBI GenInfo Identifier:294862479
NCBI Gene ID:10413
NCBI Accession:P46937.2
UniProt Secondary Accession:P46937,Q7Z574, B4DTY1, B7ZA01, E3WEB5, E3WEB6, E9PRV2 F5H202, K0KQ18, K0KYZ8, K0L195, K0L1G3,
UniProt Related Accession:P46937
Molecular Weight:504
NCBI Full Name:Transcriptional coactivator YAP1
NCBI Synonym Full Names:Yes-associated protein 1
NCBI Official Symbol:YAP1  
NCBI Official Synonym Symbols:YAP; YKI; COB1; YAP2; YAP65  
NCBI Protein Information:transcriptional coactivator YAP1; yorkie homolog; protein yorkie homolog; yes-associated protein 2; 65 kDa Yes-associated protein; yes-associated protein YAP65 homolog
UniProt Protein Name:Transcriptional coactivator YAP1
UniProt Synonym Protein Names:Protein yorkie homolog; Yes-associated protein YAP65 homolog
Protein Family:Transcriptional coactivator
UniProt Gene Name:YAP1  
UniProt Entry Name:YAP1_HUMAN

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