The Recombinant Histone H1 (CT) Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C311171) against Histone H1. Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human samples.
This antibody is suitable for WB, IHC, IF and FCM applications. It has been validated by WB analysis of HeLa, MCF-7, IHC analysis of Human breast, Human colon cancer, IF analysis of HeLa and FCM analysis of HeLa. The target is localized to the nucleus.
