The Recombinant SH-PTP1 Monoclonal Antibody is a recombinant rabbit monoclonal antibody (clone C110816) against SH-PTP1. The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. Produced by recombinant technology in Rabbit hosts and purified by Protein A affinity chromatography, this Rabbit IgG antibody is reactive against Human, Mouse and Rat samples.
This antibody is suitable for WB, IHC, IF and ELISA applications. It has been validated by IHC analysis of Human tonsil. The target is localized to the cytoplasm, nucleus, in neurons, translocates into the nucleus after treatment with angiotensin II (By similarity). Shuttles between the cytoplasm and nucleus via its association with PDPK1.
Product Name:
Recombinant SH-PTP1 Monoclonal Antibody
SKU:
RMEA0817
Size:
50 µL, 100 µL
Antibody Type:
Recombinant Monoclonal Antibody
Synonyms:
70Z-SHP, CTCN, CTCN6, EC 3.1.3.48, HCP, HCPH, Hematopoietic cell phosphatase, Hematopoietic cell protein tyrosine phosphatase, Hematopoietic Cell Protein-Tyrosine Phosphatase, HPTP1C, Protein tyrosine phosphatase 1C, Protein tyrosine phosphatase non receptor type 6, Protein tyrosine phosphatase SHP1, Protein-Tyrosine Phosphatase 1C, Protein-Tyrosine Phosphatase SHP, protein-tyrosine phosphatase SHP 1, Protein-Tyrosine Phosphatase SHP-1, PTN6, PTP 1C, PTP-1C, PTP1C, PTPN, PTPN6, SH PTP 1, SH PTP1, SH-PTP, SH-PTP1, SHP, SHP 1, SHP 1L, SHP-1, SHP-1L, SHP1, SHP1L, Src homology region 2 domain-containing phosphatase-1, tyrosine protein phosphatase non receptor type 6, Tyrosine-Protein Phosphatase Non-Receptor Type, Tyrosine-Protein Phosphatase Non-Receptor Type 6
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant Human SH-PTP1 protein
Applications:
WBIHCIFELISA
Clonality:
Recombinant Monoclonal
Clone No:
C110816
Host:
Rabbit
Isotype:
Rabbit IgG
Target:
SH-PTP1
Conjugation:
Unconjugated
Recommended Dilution:
IHC 1:500-1000; WB 1:2000-10000; IF 1:200-1000; ELISA 1:5000-20000
UniProt:
P29350
Purification:
Protein A
Concentration:
0.2 mg/mL
Buffer:
PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.
Storage:
Store at -20°C valid for 12 months. Avoid freeze / thaw cycles.
Immunohistochemistry of paraffin-embedded human tonsil using Recombinant SH-PTP1 Monoclonal Antibody at dilution of 1:200.
