The SR-BI Monoclonal Antibody (CAB0827) is a high-quality antibody developed for reliable detection and analysis of target proteins. This monoclonal antibody, generated from rabbit cells, exhibits high specificity and sensitivity for detecting SCARB1 in human samples, making it a valuable asset for research in cardiovascular disease, lipid disorders, and metabolic syndrome.SCARB1, also known as scavenger receptor class B member 1, plays a key role in mediating the uptake of cholesterol from HDL particles, thus influencing cholesterol levels and atherosclerosis development. Research on SCARB1 is essential for understanding the mechanisms underlying lipid metabolism and cardiovascular health, offering insights into potential therapeutic targets for managing dyslipidemia and cardiovascular risk.
This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
SR-BI Monoclonal Antibody
SKU:
CAB0827
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0334
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The protein encoded by this gene is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2 and facilitates cell entry by the virus, SARS-CoV2.
Purification Method
Affinity purification
Gene ID
949
RRID
AB_2861480
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SR-BI Rabbit mAb (CAB0827) at 1:2000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): BeWo Exposure time: 45s.
Immunohistochemistry analysis of paraffin-embedded Mouse liver tissue using SR-BI Rabbit mAb (CAB0827) at a dilution of 1:1000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Mouse liver tissue using SR-BI Rabbit mAb (CAB0827) at a dilution of 1:1000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Human liver cancer tissue using SR-BI Rabbit mAb (CAB0827) at a dilution of 1:1000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
Immunohistochemistry analysis of paraffin-embedded Rat liver tissue using SR-BI Rabbit mAb (CAB0827) at a dilution of 1:1000 (40x lens). High pressure antigen retrieval performed with 0.01M Tris-EDTA Buffer (pH 9.0) prior to IHC staining.
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