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5T4 Rabbit Polyclonal Antibody (CAB14790)

SKU:
CAB14790
Product Type:
Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:5T4 Rabbit Polyclonal Antibody
SKU:CAB14790
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 32-350 of human 5T4 (NP_006661.1).
Sequence:SSPT SSAS SFSS SAPF LASA VSAQ PPLP DQCP ALCE CSEA ARTV KCVN RNLT EVPT DLPA YVRN LFLT GNQL AVLP AGAF ARRP PLAE LAAL NLSG SRLD EVRA GAFE HLPS LRQL DLSH NPLA DLSP FAFS GSNA SVSA PSPL VELI LNHI VPPE DERQ NRSF EGMV VAAL LAGR ALQG LRRL ELAS NHFL YLPR DVLA QLPS LRHL DLSN NSLV SLTY VSFR NLTH LESL HLED NALK VLHN GTLA ELQG LPHI RVFL DNNP WVCD CHMA DMVT WLKE TEVV QGKD RLTC AYPE KMRN RVLL ELNS ADLD CDPI LPP
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:5T4; M6P1; 5T4AG; WAIF1
Positive Sample:Mouse brain,Mouse heart,Rat brain,Rat heart,Rat liver
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Single-pass type I membrane protein.
Calculated MW:46kDa
Observed MW:46kDa

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Purification Method:Affinity purification
Gene ID:7162
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using 5T4 Rabbit pAb (CAB14790) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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