Anti-WFDC2 Antibody (CAB6788)

Antibody Name:	Anti-WFDC2 Antibody
Antibody SKU:	CAB6788
Antibody Size:	20uL, 50uL, 100uL
Application:	IHC
Reactivity:	Human, Mouse, Rat
Host Species:	Rabbit
Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 24-124 of human WFDC2 (NP_006094.3).

Application:	IHC
Recommended Dilution:	IHC 1:100 - 1:200
Reactivity:	Human, Mouse, Rat
Positive Samples:

Immunogen:	Recombinant fusion protein containing a sequence corresponding to amino acids 24-124 of human WFDC2 (NP_006094.3).
Purification Method:	Affinity purification
Storage Buffer:	Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:	IgG
Sequence:	LVSG TGAE KTGV CPEL QADQ NCTQ ECVS DSEC ADNL KCCS AGCA TFCS LPND KEGS CPQV NINF PQLG LCRD QCQV DSQC PGQM KCCR NGCG KVSC VTPN F
Gene ID:	10406
Uniprot:	Q14508
Cellular Location:	Secreted
Calculated MW:	8kDa/11kDa/12kDa
Observed MW:	Refer to figures

Synonyms:

WFDC2, EDDM4, HE4, WAP5, dJ461P17.6

Background:

This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.

UniProt Protein Function:	WFDC2: a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
UniProt Protein Details:	Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: extracellular space Molecular Function:serine-type endopeptidase inhibitor activity; aspartic-type endopeptidase inhibitor activity; endopeptidase inhibitor activity; cysteine protease inhibitor activity Biological Process: spermatogenesis; proteolysis
NCBI Summary:	This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation. [provided by RefSeq, Jul 2008]
UniProt Code:	Q14508
NCBI GenInfo Identifier:	20141958
NCBI Gene ID:	10406
NCBI Accession:	Q14508.2
UniProt Secondary Accession:	Q14508,Q6IB27, Q8WXV9, Q8WXW0, Q8WXW1, Q8WXW2, Q96KJ1 A2A2A5, A2A2A6, A6PVD5,
UniProt Related Accession:	Q14508
Molecular Weight:	124
NCBI Full Name:	WAP four-disulfide core domain protein 2
NCBI Synonym Full Names:	WAP four-disulfide core domain 2
NCBI Official Symbol:	WFDC2
NCBI Official Synonym Symbols:	HE4; WAP5; EDDM4; dJ461P17.6
NCBI Protein Information:	WAP four-disulfide core domain protein 2; epididymal protein 4; epididymal secretory protein E4; putative protease inhibitor WAP5; WAP domain containing protein HE4-V4; major epididymis-specific protein E4; epididymis-specific, whey-acidic protein type, four-disulfide core
UniProt Protein Name:	WAP four-disulfide core domain protein 2
UniProt Synonym Protein Names:	Epididymal secretory protein E4; Major epididymis-specific protein E4; Putative protease inhibitor WAP5
Protein Family:	WAP four-disulfide core domain protein
UniProt Gene Name:	WFDC2
UniProt Entry Name:	WFDC2_HUMAN

	Immunohistochemistry of paraffin-embedded human stomach using WFDC2 antibody (CAB6788) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded mouse stomach using WFDC2 antibody (CAB6788) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded rat heart using WFDC2 antibody (CAB6788) at dilution of 1:100 (40x lens).
	Immunohistochemistry of paraffin-embedded human prostate using WFDC2 antibody (CAB6788) at dilution of 1:100 (40x lens).

ELISA Kits

Human WAP four-disulfide core domain protein 2 (WFDC2) ELISA Kit

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)