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Abatacept (Research-Grade) - Bioactivity-binding
Key Features

Abatacept (Research-Grade) (GXBS00525)

Datasheet MSDS
SKU GXBS00525
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Human
Applications ELISA, FACS, Functional assay, Research in vivo
Isotype IgG1-Fc
$832 - $2,827

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Description

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Abatacept (Research-Grade)

Abatacept (Research-Grade) is a research-grade biosimilar monoclonal antibody targeting CD80. It is a human IgG1-Fc antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Cytotoxic T-lymphocyte protein 4 (CD80/B7-1 & CD86) is a ~24 kDa protein. Inhibitory receptor acting as a major negative regulator of T-cell responses. Acts as a decoy receptor: the affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

Product Name:Abatacept (Research-Grade)
SKU:GXBS00525
Size:100 µg, 1 mg
Antibody Type:Monoclonal Antibody
Target:CD80
Isotype:IgG1-Fc
Host Species:Human
Reactivity:Human
Applications:ELISA, FACS, Functional assay, Research in vivo
Expression Host:Mammalian cells
Synonyms:CD80, BB1, T-lymphocyte activation antigen CD80, CD28LG, B7, CD28LG1, LAB7, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, BU63, B70, CD28LG2, CTLA-4 counter-receptor B7.2, Activation B7-2 antigen, T-lymphocyte activation antigen CD86, CD86, FUN-1
Purity:>95% purity as determined by SDS-PAGE.
Endotoxin Level:< 10 EU/mg
Formulation:0.01M PBS pH 7.4
State of Matter:Liquid
Regulatory Status:For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:Protein A/G purified from cell culture supernatant.
Storage and Handling:Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
UniProt:P16410, CAS: 332348-12-6
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