Abdakibart Antibody is a research-grade biosimilar antibody targeting IL1B/IL1F2. It is a human IgG4, kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry and functional assays. Endotoxin: < 10 EU/mg. Purity: >95% as determined by SDS-PAGE. For research use only.
Interleukin-1 beta is a ~30 kDa protein. Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6.
Product Name:
Abdakibart Antibody
SKU:
GXBS02639
Size:
100 µg, 1 mg
Target:
IL1B/IL1F2
Isotype:
IgG4, kappa
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FACS, Functional assay
Synonyms:
CAS: 3034641-53-4
Purity:
>95% as determined by SDS-PAGE
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
Regulatory Status:
For research use only.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
