Aldafermin (Research-Grade) is a research-grade biosimilar monoclonal antibody targeting FGF19. Format: Recombinant human FGF19 analogs.. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Fibroblast growth factor 19 (FGF19) is a ~24 kDa protein. Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4.
Product Name:
Aldafermin (Research-Grade)
SKU:
GXBS02452
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
FGF19
Isotype:
Recombinant human FGF19 analogs.
Reactivity:
Human
Applications:
ELISA, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
NGM282
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4.
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Purified by Nickel column.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
