Alginate Antibody [3G4-1F5] is a mouse monoclonal antibody directed against Alginate, offered by Assay Genie for research applications. Reported applications include WB and IHC. Reactivity is species independent. Supplied as IgG1 Kappa, purified by Protein G.
Alginate, a naturally derived polysaccharide from brown seaweed, is widely used in biomedical research due to its excellent biocompatibility, low immunogenicity, and ability to form hydrogels through ionic crosslinking with divalent cations such as calcium (Ca²⁺). In neuroscience and neurodegenerative disease research, alginate-based systems are gaining traction as advanced platforms for cell encapsulation, controlled drug delivery, and 3D neural tissue modeling. One of alginate’s most impactful applications is in the formation of microspheres and scaffolds that enable sustained, localized delivery of neuroprotective proteins and therapeutic agents. This controlled release capability is critical for maintaining therapeutic concentrations in the brain microenvironment, particularly in diseases such as Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis (ALS), where targeted intervention is essential. Moreover, alginate hydrogels support the encapsulation and transplantation of neural stem cells and glial cells, preserving cell viability and function while minimizing immune rejection. These properties make alginate an ideal candidate for developing bioengineered neural tissues, in vitro brain models, and regenerative therapies aimed at restoring damaged neural circuits. As research advances, alginate continues to emerge as a key biomaterial in the design of next-generation neurotherapeutic strategies, offering promising avenues for both fundamental neuroscience and translational applications in neurodegenerative disease treatment. This antibody is also available conjugated to ATTO 390, ATTO 488, ATTO 594, APC, Biotin, FITC, HRP, PerCP and RPE. Supplied in 100 µg. For research use only; not for diagnostic or therapeutic procedures.
Product Name:
Alginate Antibody [3G4-1F5]
Product SKU:
STMA00061
Size:
100 µg
Target:
Alginate
Host Species:
Mouse
Antibody Type:
Monoclonal
Clone ID:
3G4-1F5
Research Areas:
Cell Signaling, Post-translational Modifications
Buffer:
PBS pH7.4, 50% glycerol, 0.09% sodium azide
Storage & Shipping:
Store at -20°C. Shipped on Blue Ice or 4°C. Conjugated variants should be stored according to the product label.
Format:
Liquid
Applications:
WB, IHC
Antibody Isotype:
IgG1 Kappa
Purification:
Protein G Purified
Concentration:
1 mg/ml
Reactivity:
Species Independent
Recommended Dilution:
WB (1:500); optimal dilutions for assays should be determined by the user.
Specificity:
Binds selectively to a BSA-conjugated alginate, but not to unconjugated BSA.
Guarantee:
12 months from date of dispatch
Immunogen:
Sodium Alginate conjugated to KLH
Alternative Names:
Alginate, a naturally derived polysaccharide from brown seaweed, is widely used in biomedical research due to its excellent biocompatibility, low immunogenicity, and ability to form hydrogels through ionic crosslinking with divalent cations such as calcium (Ca²⁺). In neuroscience and neurodegenerative disease research, alginate-based systems are gaining traction as advanced platforms for cell encapsulation, controlled drug delivery, and 3D neural tissue modeling. One of alginate’s most impactful applications is in the formation of microspheres and scaffolds that enable sustained, localized delivery of neuroprotective proteins and therapeutic agents. This controlled release capability is critical for maintaining therapeutic concentrations in the brain microenvironment, particularly in diseases such as Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis (ALS), where targeted intervention is essential. Moreover, alginate hydrogels support the encapsulation and transplantation of neural stem cells and glial cells, preserving cell viability and function while minimizing immune rejection. These properties make alginate an ideal candidate for developing bioengineered neural tissues, in vitro brain models, and regenerative therapies aimed at restoring damaged neural circuits. As research advances, alginate continues to emerge as a key biomaterial in the design of next-generation neurotherapeutic strategies, offering promising avenues for both fundamental neuroscience and translational applications in neurodegenerative disease treatment.
References:
1. Zhai P., Chen X.B., and Schreyer D.J. (2013) Biofabrication. 5(1): 015009. 2. Selimoglu S.M., Ayyildiz-Tamis D., Gurhan I.D., and Elibol M. (2012) J Biosci Bioeng. 113(2):233-238.