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5T4 Rabbit Monoclonal Antibody (CAB19541)

SKU:
CAB19541
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
5T4
5T4AG
M6P1
WAIF1
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:5T4 Rabbit Monoclonal Antibody
SKU:CAB19541
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 321-420 of human 5T4 (Q13641).
Sequence:LTCA YPEK MRNR VLLE LNSA DLDC DPIL PPSL QTSY VFLG IVLA LIGA IFLL VLYL NRKG IKKW MHNI RDAC RDHM EGYH YRYE INAD PRLT NLSS NSDV
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:5T4; M6P1; 5T4AG; WAIF1
Positive Sample:A549,MCF7
Conjugate:Unconjugated
Cellular Localization:Plasma membrane
Calculated MW:46kDa
Observed MW:75kDa

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Purification Method:Affinity purification
Gene ID:7162
Clone Number:ARC2167
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using 5T4 Rabbit mAb (CAB19541) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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