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Cardiac Troponin C Rabbit Monoclonal Antibody (CAB3816)

SKU:
CAB3816
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CMD1Z
CMH13
TN-C
TNC
TNNC
Research Area:
Cell Biology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Cardiac Troponin C Rabbit Monoclonal Antibody
SKU:CAB3816
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TNNC1 (P63316).
Sequence:MDDI YKAA VEQL TEEQ KNEF KAAF DIFV LGAE DGCI STKE LGKV MRML GQNP TPEE LQEM IDEV DEDG SGTV DFDE FLVM MVRC MKDD SKGK SEEE LSDL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:TNC; TN-C; TNNC; CMD1Z; CMH13; TNNC1
Positive Sample:Mouse heart,Rat heart
Conjugate:Unconjugated
Cellular Localization:cytosol
Calculated MW:18kDa
Observed MW:18kDa

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.

Purification Method:Affinity purification
Gene ID:7134
Clone Number:ARC0840
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using TNNC1 Rabbit mAb (CAB3816) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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