Anti-CLPP Antibody (CAB3214)
- SKU:
- CAB3214
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DFNB81
- PRLTS3
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Product Name: | CLPP Rabbit mAb |
| Product Code: | CAB3214 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | DFNB81, PRLTS3 |
| Applications: | WB, IHC, IF |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human CLPP |
| Applications: | WB, IHC, IF |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, SW620, HepG2, Mouse liver, Mouse heart, Rat liver |
| Immunogen: | A synthesized peptide derived from human CLPP |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 8192 |
| Uniprot: | Q16740 |
| Calculated MW: | 26kDa |
| Observed MW: | 26kDa |
| UniProt Protein Function: | Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. |
| NCBI Summary: | The protein encoded by this gene belongs to the peptidase family S14 and hydrolyzes proteins into small peptides in the presence of ATP and magnesium. The protein is transported into mitochondrial matrix and is associated with the inner mitochondrial membrane. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q16740 |
| NCBI GenInfo Identifier: | 5174419 |
| NCBI Gene ID: | 8192 |
| NCBI Accession: | NP_006003 |
| UniProt Secondary Accession: | Q16740,B2R4W5, |
| UniProt Related Accession: | Q16740 |
| Molecular Weight: | 24.2kDa (222aa), confirmed by MALDI-TOF |
| NCBI Full Name: | ATP-dependent Clp protease proteolytic subunit, mitochondrial |
| NCBI Synonym Full Names: | caseinolytic mitochondrial matrix peptidase proteolytic subunit |
| NCBI Official Symbol: | CLPPÂ Â |
| NCBI Official Synonym Symbols: | DFNB81; PRLTS3Â Â |
| NCBI Protein Information: | ATP-dependent Clp protease proteolytic subunit, mitochondrial |
| UniProt Protein Name: | ATP-dependent Clp protease proteolytic subunit, mitochondrial |
| UniProt Synonym Protein Names: | Endopeptidase Clp |
| Protein Family: | ATP-dependent Clp protease proteolytic |
| UniProt Gene Name: | CLPPÂ Â |
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