The CD21 Monoclonal Antibody (CAB1267) is a high-quality antibody developed for reliable detection and analysis of target proteins. This polyclonal antibody, generated in rabbits, is highly specific for human samples and is validated for use in various applications, including Western blotting.CD21, also known as complement receptor 2 (CR2), is involved in the regulation of B cell activation and immune responses. It serves as a receptor for complement component C3d, which facilitates antigen presentation and enhances the immune response. By targeting CD21 with this antibody, researchers can study its expression and function in different cell types, providing insights into its role in immunology and potential implications in conditions such as autoimmune diseases and infections.
This antibody is validated for use in WB, ELISA, IF-P applications and has demonstrated reactivity against Human, Rat samples.
Product Name:
CD21 Monoclonal Antibody
SKU:
CAB1267
Size:
20μL, 100μL
Reactivity:
Human, Rat
Clone Number:
ARC1868
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method
Affinity purification
Gene ID
1380
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using CR2/CD21 Rabbit mAb (CAB1267) at 1:5000 dilution incubated overnight at 4℃. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25 μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Negative control (NC): K-562. Exposure time: 20 s.
Immunofluorescence analysis of paraffin-embedded rat spleen using CR2/CD21 Rabbit mAb (CAB1267) at dilution of 1:100 (40x lens). Secondary antibody: Cy3-conjugated Goat anti-Rabbit IgG (H+L) (CABS007) at 1:500 dilution. Blue: DAPI for nuclear staining.
