Anti-DENV-2 E-DII/Envelope Protein E Recombinant Monoclonal Antibody (2A10)
Anti-DENV-2 E-DII/Envelope Protein E Recombinant Monoclonal Antibody (2A10) is a recombinant monoclonal antibody targeting DENV-2 E-DII/Envelope Protein E (clone 2A10). It is a mouse IgG2a antibody. Reactivity: Dengue Virus (DENV1-4), Yellow Fever Virus (YFV), Zika virus (ZIKV), West Nile virus (WNV). Supplied as a liquid in 0.01M PBS, pH 7.4. Applications: ELISA and neutralization assays. Purity: >95% as determined by SDS-PAGE. For research use only.
Genome polyprotein (E-DII) is a ~378 kDa protein. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA (Probable). Plays a role in virus budding by binding to the cell membrane and gathering the viral RNA into a nucleocapsid that forms the core of a mature virus particle. During virus entry, may induce genome penetration into the host cytoplasm after hemifusion induced by the surface proteins. Can migrate to the cell nucleus where it modulates host functions.
Product Name:
Anti-DENV-2 E-DII/Envelope Protein E Recombinant Monoclonal Antibody (2A10)