Anti-HBsAg Reference Antibody (OST 577) is a research-grade biosimilar monoclonal antibody targeting Large envelope protein. It is a human IgG1-lambda antibody. Reactivity: Hepatitis B virus (HBV). Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Large envelope protein (HBsAg) is a ~42 kDa protein. The large envelope protein exists in two topological conformations, one which is termed 'external' or Le-HBsAg and the other 'internal' or Li-HBsAg. In its external conformation the protein attaches the virus to cell receptors and thereby initiating infection. This interaction determines the species specificity and liver tropism. This attachment induces virion internalization predominantly through caveolin-mediated endocytosis. The large envelope protein also assures fusion between virion membrane and endosomal membrane.
Product Name:
Anti-HBsAg Reference Antibody (OST 577)
SKU:
GXBS02254
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Clone:
OST 577
Target:
Large envelope protein
Isotype:
IgG1-lambda
Host Species:
Human
Reactivity:
Hepatitis B virus (HBV)
Applications:
ELISA, FACS, Functional assay, Research in vivo
Expression Host:
Mammalian cells
Synonyms:
OST577, OST577, OST-577
Recommended Dilutions:
ELISA: 1:2000-1:20000
Purity:
>95% purity as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
