Anti-Human CD45/PTPRC Recombinant Nanobody (2H5) is a recombinant nanobody targeting Human CD45/PTPRC (clone 2H5). Format: VHH-8His-Cys-tag (alpaca host). Reactivity: Human. Supplied as a liquid in 0.01M PBS, pH 7.4. Applications: ELISA and SPR. Purity: >95% as determined by SDS-PAGE. For research use only.
Receptor-type tyrosine-protein phosphatase C (CD45/PTPRC) is a ~144 kDa protein. Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.
Product Name:
Anti-Human CD45/PTPRC Recombinant Nanobody (2H5)
Size:
50 µg, 100 µg, 1 mg
Product SKU:
GXRM04000
Target:
Receptor-type tyrosine-protein phosphatase C
Host Species:
Alpaca
Antibody Type:
Monoclonal
Clone ID:
2H5
Reactivity:
Human
Buffer:
0.01M PBS pH 7.4
Storage & Shipping:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Format:
Liquid
Applications:
ELISA, SPR
Recommended Dilutions:
ELISA: 1:2000-1:20000
Antibody Isotype:
VHH-8His-Cys-tag
Purity:
>95% as determined by SDS-PAGE.
Purification:
Protein A/G purified from cell culture supernatant.
