Anti-Human CD72 Recombinant Nanobody (NbD4) is a recombinant nanobody targeting Human CD72 (clone NbD4). Format: VHH-8His-Cys-tag (alpaca host). Reactivity: Human. Supplied as a liquid in 0.01M PBS, pH 7.4. Applications: ELISA. Purity: >95% as determined by SDS-PAGE. For research use only.
B-cell differentiation antigen CD72 is a ~40 kDa protein. Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis.
Product Name:
Anti-Human CD72 Recombinant Nanobody (NbD4)
Size:
50 µg, 100 µg, 1 mg
Product SKU:
GXRM04005
Target:
CD72
Host Species:
Alpaca
Antibody Type:
Monoclonal
Clone ID:
NbD4
Reactivity:
Human
Buffer:
0.01M PBS pH 7.4.
Storage & Shipping:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Format:
Liquid
Applications:
ELISA
Recommended Dilutions:
ELISA: 1:2000-1:20000
Antibody Isotype:
VHH-8His-Cys-tag
Purity:
>95% as determined by SDS-PAGE.
Purification:
Protein A/G purified from cell culture supernatant.
