Anti-Human CD8 Recombinant Nanobody (SAA2076) is a recombinant nanobody targeting Human CD8 (clone SAA2076). Format: VHH-Cys (alpaca host). Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA. Purity: >95% as determined by SDS-PAGE. For research use only.
T-cell surface glycoprotein CD8 alpha chain (CD8A) is a ~25 kDa protein. Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex.
Product Name:
Anti-Human CD8 Recombinant Nanobody (SAA2076)
Size:
50 µg, 100 µg, 1 mg
Product SKU:
GXRM04815
Target:
T-cell surface glycoprotein CD8 alpha chain
Host Species:
Alpaca
Antibody Type:
Monoclonal
Clone ID:
SAA2076
Reactivity:
Human
Buffer:
0.01M PBS pH 7.4
Storage & Shipping:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
