Human IgA Rabbit Monoclonal Antibody (CAB19704)
- SKU:
- CAB19704
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- IgA1
Description
Product Name: | Human IgA Rabbit Monoclonal Antibody |
SKU: | CAB19704 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-353 of human IgA (P01876). |
Sequence: | ASPT SPKV FPLS LCST QPDG NVVI ACLV QGFF PQEP LSVT WSES GQGV TARN FPPS QDAS GDLY TTSS QLTL PATQ CLAG KSVT CHVK HYTN PSQD VTVP CPVP STPP TPSP STPP TPSP SCCH PRLS LHRP ALED LLLG SEAN LTCT LTGL RDAS GVTF TWTP SSGK SAVQ GPPE RDLC GCYS VSSV LPGC AEPW NHGK TFTC TAAY PESK TPLT ATLS KSGN TFRP EVHL LPPP SEEL ALNE LVTL TCLA RGFS PKDV LVRW LQGS QELP REKY LTWA SRQE PSQG TTTF AVTS ILRV AAED WKKG DTFS CMVG HEAL PLAF TQKT IDRL AGKP THVN VSVV MAEV DGTC Y |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | IgA1; Human IgA |
Positive Sample: | Human plasma |
Conjugate: | Unconjugated |
Cellular Localization: | blood microparticle, external side of plasma membrane, extracellular exosome, extracellular region, extracellular space, immunoglobulin complex, circulating |
Calculated MW: | 60kDa |
Observed MW: | 55kDa |
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen. Ig alpha is the major immunoglobulin class in body secretions.
Purification Method: | Affinity purification |
Gene ID: | 3493/3494 |
Clone Number: | ARC2239 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |