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Anti-Human PHOX2B Monoclonal Antibody (1A547) - SDS-PAGE
Key Features

Anti-Human PHOX2B Monoclonal Antibody (1A547) (GXMA00521)

SKU GXMA00521
Product Type Antibody
Antibody Type Monoclonal
Host Species Mouse
Reactivity Human
Applications ELISA, IHC, WB
Clone ID 1A547
Isotype IgG
$434 - $595

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Description

Anti-Human PHOX2B Monoclonal Antibody (1A547)

Anti-Human PHOX2B Monoclonal Antibody (1A547) is a mouse monoclonal antibody of isotype IgG. Immunogen: E. coli - derived recombinant human PHOX2B (Thr106-Gly173). Target: Paired mesoderm homeobox protein 2B, Neuroblastoma Phox, NBPhox, PHOX2B homeodomain protein, Paired-like homeobox 2B, PHOX2B. Species reactivity: Human. Applications: ELISA, IHC, WB. Protein A/G purified from cell culture supernatant. Supplied as a liquid in 0.01M PBS, pH 7.4.

Paired mesoderm homeobox protein 2B (PHOX2B) is a ~31 kDa protein. Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

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