Anti-IRAK4 Antibody (CAB20839)
- SKU:
- CAB20839
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Antibody Name: | Anti-IRAK4 Antibody (CAB20839) |
| Antibody SKU: | CAB20839 |
| Antibody Size: | 50µL, 100µL |
| Application: | Western blotting |
| Reactivity: | Human |
| Host Species: | Rabbit |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IRAK4 (NP_057207.2). |
| Application: | Western blotting |
| Recommended Dilution: | WB 1:500 - 1:2000 |
| Reactivity: | Human |
| Positive Samples: | Jurkat |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human IRAK4 (NP_057207.2). |
| Purification Method: | Affinity purification |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | MNKP ITPS TYVR CLNV GLIR KLSD FIDP QEGW KKLA VAIK KPSG DDRY NQFH IRRF EALL QTGK SPTS ELLF DWGT TNCT VGDL VDLL IQNE FFAP ASLL LPDA VPKT ANTL PSKE AITV QQKQ MPFC DKDR TLMT PVQN LEQS YMPP DSSS PENK SLEV SDTR FHSF SFYE LKNV TNNF DERP ISVG GNKM GEGG FGVV |
| Cellular Location: | Cytoplasm |
| Calculated MW: | 37kDa/51kDa |
| Observed MW: | 55KDa |
| Synonyms: | IRAK4, IPD1, IRAK-4, NY-REN-64, REN64 |
| Background: | This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
 | Western blot analysis of extracts of Jurkat cells, using IRAK4 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 45s. |
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