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Anti-MARK2 Antibody CAB6512
Key Features

MARK2 Rabbit Monoclonal Antibody (CAB6512)

Datasheet MSDS
SKU CAB6512
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Human, Mouse, Rat
Host Species Rabbit
Synonyms EMK1, EMK-1, PAR-1, Par1b, Par-1b, MARK2
Research Use Developmental Biology
€131 - €457

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Description

system_update_altDatasheetsystem_update_altMSDS

MARK2 Monoclonal Antibody (CAB6512)

The MARK2 Monoclonal Antibody (CAB6512) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, derived from rabbit serum, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the Mark2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable asset for studies in cell biology and cancer research.Mark2, also known as Par-1c, plays a pivotal role in cell signaling pathways that regulate cell polarity, migration, and cell cycle progression.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.

Product Name:MARK2 Monoclonal Antibody
SKU:CAB6512
Size:20μL, 100μL
Reactivity:Human, Mouse, Rat
Clone Number:ARC1862
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:KPRS LRFT WSMK TTSS MEPN EMMR EIRK VLDA NSCQ SELH EKYM LLCM HGTP GHED FVQW EMEV CKLP RLSL NGVR FKRI SGTS MAFK NIAS KIAN ELKL
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:EMK1, EMK-1, PAR-1, Par1b, Par-1b, MARK2
Positive Sample:BT-474, Raji, Mouse brain, Rat brain
Cellular Localization:Cell Membrane, Cytoplasm, Lateral Cell Membrane, Peripheral Membrane Protein, Cytoskeleton.
Calculated MW:88kDa
Observed MW:78kDa/82kDa

This gene encodes a member of the Par-1 family of serine/threonine protein kinases. The protein is an important regulator of cell polarity in epithelial and neuronal cells, and also controls the stability of microtubules through phosphorylation and inactivation of several microtubule-associating proteins. The protein localizes to cell membranes. Multiple transcript variants encoding different isoforms have been found for this gene.

Purification MethodAffinity purification
Gene ID2011
RRIDAB_2863529
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using MARK2 Rabbit mAb (CAB6512) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 3s.
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