Anti-Mouse CD200 [OX-90] In Vivo Antibody - Low Endotoxin
Introducing the Anti-Mouse CD200 [OX-90] In Vivo Antibody - Low Endotoxin from Assay Genie, a highly specific monoclonal antibody designed for in vivo applications. This antibody targets the CD200 protein, crucial in immune regulation, making it ideal for research in immunology and related fields. With a rat IgG1 isotype, it ensures high purity and low endotoxin levels (<1.0 EU/mg), perfect for ELISA, flow cytometry, immunohistochemistry, and other assays. Available in various sizes, it is formulated in phosphate-buffered saline (PBS) for stability and efficacy.
Enhance your research with this reliable and versatile antibody. CD200, also known as OX-2, is a membrane glycoprotein expressed on a variety of cells, including lymphocytes, neurons, and endothelial cells. It plays a significant role in down-regulating immune responses and maintaining immune homeostasis by interacting with the CD200 receptor (CD200R) on macrophages and other cells of the myeloid lineage.
Product Name:
Anti-Mouse CD200 [OX-90] In Vivo Antibody - Low Endotoxin
Product Code:
IVMB0300
Size:
1 mg, 5 mg, 25 mg, 50 mg, 100 mg
Clone:
OX-90
Protein:
CD200
Product Type:
Monoclonal Antibody
Synonyms:
OX-2
Isotype:
IgG2a
Reactivity:
Mouse
Applications:
FC, IHC, In Vivo
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Endotoxin Level:
<1.0 EU/µg as determined by the LAL method
Purity:
≥95% monomer by analytical SEC ⋅ >95% by SDS Page
Product Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Applications:
FC, IHC, In Vivo
Reactivity:
Mouse
Host Species:
Rat
Specificity:
Clone OX-90 reacts with murine CD200 (OX-2).
Antigen Distribution:
Thymocytes, neurons, B cells, splenic follicular dendritic cells and endothelium, and subsets of T cells and dendritic cells
Concentration:
≥ 5.0 mg/ml
Endotoxin Level:
<1.0 EU/µg as determined by the LAL method
Formulation:
This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Purity:
≥95% monomer by analytical SEC ⋅ >95% by SDS Page
Preparation:
Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:
Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
CD200 (OX-2) is an immune suppressor that regulates the of induction of cytokine production by conventional allostimulatory DC1,2. CD200 limits pro-inflammatory signals and has been shown to play an important role in cancer and immune disorders3,4.
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