Anti-Mouse CD229/LY9 Recombinant Monoclonal Antibody (D08) is a recombinant monoclonal antibody targeting Mouse CD229/LY9 (clone D08). It is a rabbit IgG antibody. Reactivity: Mouse. Supplied as a liquid in 0.01M PBS, pH 7.4. Applications: ELISA. Purity: >95% as determined by SDS-PAGE. For research use only.
T-lymphocyte surface antigen Ly-9 (CD229/LY9) is a ~73 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion; the costimulatory activity requires SH2D1A.
![Anti-CD229 [R02-1I0] Monoclonal Antibody (AGMB02454)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/images/stencil/590x590/products/273743/680063/anti-cd229-r02-1i0-monoclonal-antibody-agmb02454__37792.1773040931.jpg?c=2 "Anti-CD229 [R02-1I0] Monoclonal Antibody (AGMB02454)")
