The NR1D2 Antibody (CAB20447) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity for human samples and is validated for use in Western blotting applications. By targeting the NR1D2 protein, this antibody allows for the visualization and analysis of NR1D2 expression in a variety of cell types, making it an essential component of studies in chronobiology and metabolic research.NR1D2, also known as Rev-erb alpha, is a key regulator of the circadian clock and metabolic pathways, influencing processes such as energy metabolism, lipid homeostasis, and glucose regulation.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
NR1D2 Antibody
SKU:
CAB20447
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Mouse lung, Mouse brain, Mouse skeletal muscle, Rat lung, Rat skeletal muscle, Rat heart
Cellular Localization:
Cytoplasm, Nucleoplasm, Nucleus.
Calculated MW:
65kDa
Observed MW:
70kDa
This gene encodes a member of the nuclear hormone receptor family, specifically the NR1 subfamily of receptors. The encoded protein functions as a transcriptional repressor and may play a role in circadian rhythms and carbohydrate and lipid metabolism. Alternatively spliced transcript variants have been described.
Purification Method
Affinity purification
Gene ID
9975
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using Rev-erb beta/NR1D2 Rabbit pAb (CAB20447) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
