Anti-p16 ARC Antibody (CAB4794)

SKU:
CAB4794
€129 - €349

Description

Technical Manual

Anti-p16 ARC Antibody

Product Name: Anti-p16 ARC Antibody
Product SKU: CAB4794
Size: 20uL, 50 uL
Host Species: Rabbit
Purification Method: Affinity purification
Isotype: IgG
Background:

This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]

Immunogen: A synthesized peptide derived from human p16 ARC
Sequence:

Email for sequence

Gene ID: 10092
Swiss Prot: O15511
Synonyms: ARC16; dJ127C7.3; p16-Arc
Calculated MW: 16kDa
Observed MW: 18KDa
Reactivity: Human, Mouse, Rat
Application: WB
Recommended Dilution: WB 1:500 - 1:2000
Storage Buffer: Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Application Key: Western blotting
Positive Samples: 293T, Mouse brain, Mouse thymus, Rat brain, Rat thymus
Cellular Location:  

Product Images

Anti-p16 ARC Antibody (CAB4794)

Western blot - p16 ARC Rabbit mAb (CAB4794)

Uniprot Information

UniProt Protein Function: ARPC5: Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Belongs to the ARPC5 family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 1q25.3

Cellular Component: actin cytoskeleton; Arp2/3 protein complex; cytoplasm; cytosol; extracellular region; focal adhesion

Molecular Function:actin filament binding; protein binding; structural constituent of cytoskeleton

Biological Process: actin cytoskeleton organization and biogenesis; cell migration; cell motility; ephrin receptor signaling pathway; neutrophil degranulation

NCBI Summary: This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
UniProt Code: O15511
NCBI GenInfo Identifier: 3121767
NCBI Gene ID: 10092
NCBI Accession: O15511.3
UniProt Secondary Accession: O15511,Q6PG42, A6NEC4,
UniProt Related Accession: O15511
Molecular Weight: 16kDa
NCBI Full Name: Actin-related protein 2/3 complex subunit 5
NCBI Synonym Full Names: actin related protein 2/3 complex subunit 5
NCBI Official Symbol: ARPC5
NCBI Official Synonym Symbols: ARC16; p16-Arc; dJ127C7.3
NCBI Protein Information: actin-related protein 2/3 complex subunit 5
UniProt Protein Name: Actin-related protein 2/3 complex subunit 5
UniProt Synonym Protein Names: Arp2/3 complex 16 kDa subunit; p16-ARC
UniProt Gene Name: ARPC5
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Additional Information

Product type:
Antibody
Reactivity:
Human
Reactivity:
Mouse
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Biology
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