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Anti-Septin 2 Antibody (CAB7163)

SKU:
CAB7163
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
DIFF6
NEDD-5
NEDD5
Pnutl3
hNedd5
Research Area:
Cell Cycle
€139 - €419
Frequently bought together:

Description

Product Name:Septin 2 Rabbit mAb
Product Code:CAB7163
Size:20uL, 50uL, 100uL
Synonyms:DIFF6, NEDD-5, NEDD5, Pnutl3, hNedd5
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human Septin 2
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:PC-3, SH-SY5Y, Mouse testis, Mouse brain, Rat brain
Immunogen:A synthesized peptide derived from human Septin 2
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4735
Uniprot:Q15019
Cellular Location:Cell projection, Chromosome, Cleavage furrow, Cytoplasm, Midbody, cell cortex, centromere, cilium membrane, cytoskeleton, kinetochore, spindle
Calculated MW:41kDa
Observed MW:45kDa
UniProt Protein Function:SEPT2: a member of the septin family of proteins. May be involved in the process of cytokinesis. Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localized to fibrous or granular structures, depending on the growth state of the cell.
UniProt Protein Details:

Protein type:Cytoskeletal; Hydrolase; Cell development/differentiation; Motility/polarity/chemotaxis; Cell cycle regulation

Chromosomal Location of Human Ortholog: 2q37

Cellular Component: nucleoplasm; perinuclear region of cytoplasm; cytoplasm; nucleolus; exocyst; synapse; spindle; midbody; cell cortex; nucleus; actin cytoskeleton; cleavage furrow

Molecular Function:protein binding; GTP binding; protein complex scaffold; enzyme regulator activity

Biological Process: mitosis; smoothened signaling pathway; regulation of protein localization; regulation of catalytic activity; cell division; cilium biogenesis; regulation of L-glutamate transport; neurite development

UniProt Code:Q15019
NCBI GenInfo Identifier:2500769
NCBI Gene ID:4735
NCBI Accession:Q15019.1
UniProt Secondary Accession:Q15019,Q14132, Q53QU3, Q8IUK9, Q96CB0, B4DGE8,
UniProt Related Accession:Q15019
Molecular Weight:361
NCBI Full Name:Septin-2
NCBI Synonym Full Names:septin 2
NCBI Official Symbol:SEPT2  
NCBI Official Synonym Symbols:DIFF6; NEDD5; NEDD-5; Pnutl3; hNedd5  
NCBI Protein Information:septin-2; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed developmentally down-regulated protein 5
UniProt Protein Name:Septin-2
UniProt Synonym Protein Names:Neural precursor cell expressed developmentally down-regulated protein 5; NEDD-5
UniProt Gene Name:SEPT2  
UniProt Entry Name:SEPT2_HUMAN

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