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TRIM24 Monoclonal Antibody (CAB20938)

SKU:
CAB20938
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
€179 - €469
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TRIM24 Monoclonal Antibody
SKU:CAB20938
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRIM24 (O15164).
Sequence:TNNT IQFH CDPS FWAQ NIIN LGSL VIED KESQ PQMP KQNP VVEQ NSQP PSGL SSNQ LSKF PTQI SLAQ LRLQ HMQQ QVMA QRQQ VQRR PAPV GLPN PRMQ G
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA; TRIM24
Positive Sample:HepG2,Mouse testis,Rat testis
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus.
Calculated MW:117kDa
Observed MW:117kDa/140kDa

The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Purification Method:Affinity purification
Gene ID:8805
Clone Number:ARC2920
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using TRIM24 antibody (CAB20938) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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