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APC Anti-Human CD3 Antibody [UCHT1] (AGEL2466)

Datasheet MSDS
SKU AGEL2466
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone UCHT1
Conjugation APC
€30 - €144

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Description

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APC Anti-Human CD3 Antibody [UCHT1]

The Anti-Human CD3 Antibody (UCHT1) from Assay Genie is a highly specific research tool designed for studying the CD3 protein, a crucial component of the T-cell receptor complex. This monoclonal antibody, derived from mouse hybridoma cells, exhibits exceptional reactivity with human samples and is ideal for various immunological applications.CD3 is a key player in T-cell activation and signal transduction, making it a pivotal target for investigating adaptive immune responses and T-cell function. The UCHT1 antibody enables precise detection and analysis of CD3 expression in diverse cell populations, providing valuable insights into immune system dynamics and T-cell activation mechanisms.

With its validated performance in techniques such as flow cytometry, immunohistochemistry, and immunoprecipitation, the Anti-Human CD3 Antibody offers researchers a reliable tool for unraveling the complexities of T-cell biology. Whether studying basic immunology, immune disorders, or therapeutic development, this antibody is a valuable asset for advancing research in immunology, oncology, and beyond.

Product Title:APC Anti-Human CD3 Antibody [UCHT1]
SKU:AGEL2466
Size:20 Tests, 100 Tests, 200 Tests
Clone No:UCHT1
Synonyms:T-cell surface glycoprotein CD3 epsilon chain;CD3E;T-cell surface antigen T3/Leu-4 epsilon chain;CD3e;CD3E;T3E;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P07766
Gene ID:915
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD3ε is a 20 kD chain of the CD3/T cell receptor (TCR) complex, which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation.
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