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APC Anti-Mouse IL-17A Antibody [17F3] (AGEL3127)

Datasheet MSDS
SKU AGEL3127
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications ICFCM
Reactivity Mouse
Host Species Mouse
Isotype Mouse IgG1, κ
Clone 17F3
Conjugation APC
€135 - €275

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Description

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APC Anti-Mouse IL-17A Antibody [17F3]

The APC Anti-Mouse IL-17A Antibody (17F3), AGEL3127, is a cutting-edge research tool designed for investigating the role of interleukin-17A (IL-17A) in mouse immune responses. This antibody, produced against mouse IL-17A, offers high specificity and sensitivity for detecting IL-17A in various experimental settings.IL-17A is a pro-inflammatory cytokine that plays a vital role in host defense against infections and contributes to the pathogenesis of various autoimmune conditions. By targeting IL-17A, researchers can gain valuable insights into the immune mechanisms underlying inflammatory diseases such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease.

The APC Anti-Mouse IL-17A Antibody (17F3) can be utilized in techniques such as flow cytometry and immunohistochemistry to visualize IL-17A expression in immune cells and tissues. Its reliable performance and accurate detection make it an essential tool for scientists studying the complex interplay of IL-17A in immune regulation and disease progression.Unlock the potential of your research by incorporating the APC Anti-Mouse IL-17A Antibody (17F3), AGEL3127, into your experiments. Explore the intricate roles of IL-17A in immune function and inflammatory disorders with confidence and precision.

Product Title:APC Anti-Mouse IL-17A Antibody [17F3]
SKU:AGEL3127
Size:25µg, 100µg
Clone No:17F3
Synonyms:Interleukin-17A;Il17a;Ctla8;
Host Species:Mouse
Reactivity:Mouse
Application:ICFCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q62386
Gene ID:16171
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-38A in vivo.
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